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Dr. Uzma Rehman


Dupuytren’s Disease



Also called Dupuytren’s Contracture, it is a thickening or knotting of the tissue just below the skin of the palm of the hand. In extreme conditions, it can pull (or contract) one or more fingers into a bent position, making it difficult to straighten them and interfering with normal hand function. Dupuytren’s Contracture is not usually painful but can lead to other conditions such as plantar fibromatosis.

Dupuytren’s Contracture is caused by a build-up of collagen, a naturally-occurring protein in the body. This collagen develops over time and can thicken into a rope-like cord in the palm. Some people mistake Dupuytren’s for arthritis or other condition.

Treatment of Dupuytren’s

Although the cause of this condition is not known, it may run in families and can be influenced by tobacco and alcohol use. Mild cases of Dupuytren’s contracture that do not have much effect on hand function may not require any treatment and can simply be monitored through regular checkups. More severe cases may benefit from surgery.

XIAFLEX is a newer treatment whereby a collagenase substance into injected into the cord. The collagenase weakens the cord so that the physician can work the hand to break it; up to three injections may be needed. There can be side effects, so the injection is administered in the doctor’s office. Follow up finger exercises may be further recommended to help with treatment.

Dupuytren’s Surgery

Typically non-surgical treatment and/or collagenase injection is recommended for Dupuytren’s, but severe cases may require surgery. Surgery involves making one or more incisions (typically along the creases of the hand) and removal of the fibrous tissue.

If you are suffering from contracture of one or more fingers, contact Dr. Rehman for an evaluation and consultation. As with most medical conditions, early detection, awareness and a comprehensive treatment plan is the most effective way to combat the effects of conditions like Dupuytren’s Contracture.


Common Conditions


- Carpal Tunnel Syndrome
- CMC and Thumb Arthritis
- DeQuervain's Disease
- Dupuytrens Contracture Disease
- Fingernail Infection
- Ganglion Cysts
- Hand, Wrist or Finger Fractures
- Hand, Wrist or Finger Pain
- Tendonitis
- Tendons and Nerves
- Tennis Elbow
- Trigger Finger
- Ulnar Nerve Neuropathy


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Carpal Tunnel Treatment | Ulnar Nerve Neuropathy | Ganglions & Cysts | Hand & Forearm Fractures | Trigger Finger | CMC & Thumb Arthritis Treatment | Dupuytren's Contracture
Tendons & Nerves | Dequervain's Disease | Fingernail Injuries & Infections


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